Concomitant Medications Taken by at Least 5% of Subjects in Any Treatment Group
Study CDISCPILOT01 — Safety Analysis Set
	Placebo	Xanomeline Low Dose	Xanomeline High Dose	
	(N=86)	(N=84)	(N=84)	
Subjects receiving at least one concomitant medication	77 (89.5%)	74 (88.1%)	78 (92.9%)	
Therapeutic class and coded medication, n (%)				
UNCODED	74 (86.0%)	70 (83.3%)	77 (91.7%)	
UNCODED	74 (86.0%)	70 (83.3%)	77 (91.7%)	
NERVOUS SYSTEM	23 (26.7%)	14 (16.7%)	8 (9.5%)	
ACETYLSALICYLIC ACID	21 (24.4%)	11 (13.1%)	6 (7.1%)	
SYSTEMIC HORMONAL PREPARATIONS, EXCL.	2 (2.3%)	13 (15.5%)	8 (9.5%)	
HYDROCORTISONE	2 (2.3%)	13 (15.5%)	8 (9.5%)	
ALIMENTARY TRACT AND METABOLISM	12 (14.0%)	11 (13.1%)	9 (10.7%)	
CALCIUM	7 (8.1%)	6 (7.1%)	3 (3.6%)	
CARDIOVASCULAR SYSTEM	12 (14.0%)	12 (14.3%)	7 (8.3%)	

Concomitant Medications Taken by at Least 5% of Subjects in Any Treatment Group
Study CDISCPILOT01 — Safety Analysis Set
	Placebo	Xanomeline Low Dose	Xanomeline High Dose	
	(N=86)	(N=84)	(N=84)	
AMLODIPINE	8 (9.3%)	1 (1.2%)	2 (2.4%)	
GENITO URINARY SYSTEM AND SEX HORMONES	6 (7.0%)	10 (11.9%)	5 (6.0%)	
ESTROGENS CONJUGATED	6 (7.0%)	10 (11.9%)	5 (6.0%)	
Reduced rendering of the same analysis results dataset as the post-text display: a coded medication is shown when at least 5% of subjects in at least one treatment group took it, and a therapeutic class is shown when at least one of its medications is.
Treatment groups are PLANNED treatment (TRT01P). Twelve subjects in this study received a treatment other than the one they were randomised to; grouping by actual treatment (TRT01A) would give column sizes of 86, 96 and 72.
A subject is counted once per therapeutic class and once per coded medication, however many records they have. Class counts are therefore not the sum of the medication counts beneath them.
Every recorded medication counts, whether it was taken before, during or after treatment. Restricting to medications taken on treatment (ONTRTFL = 'Y') would count a much smaller set of records.
UNCODED is not a therapeutic class. It is how this study's data records a medication that was never coded to a dictionary term, and it is reported rather than dropped.
Classes, and the medications within a class, are ordered by the largest subject count in any treatment group, ties alphabetically. The reference document this display targets ordered them alphabetically by class instead.
Percentages are based on the number of subjects in the safety analysis set for each treatment group.	
Source: adcm, adsl (pharmaverseadam). Data cut-off: 2014-07-01. open.csr display t-conmeds (in-text variant); generated from the committed ARD.