Open-source tools for running and monitoring clinical trials. Most of this work is still active — the links go to live docs, demos and source.

{gsm}

Creator · Technical lead, Gilead RBQM · 2022 – present

An open-source R framework for risk-based quality monitoring, designed for GxP from the first commit. Approved for GxP use and running monitoring oversight on more than 15 active studies, with a surrounding toolchain that turns validation evidence into a build artifact instead of a document nobody reads.

Docs GitHub Paper

safety.viz

Creator · 2026 · JavaScript

A charting library for monitoring clinical trial safety: thirteen interactive charts, from safety histograms to the eDISH hepatic explorer, the nephrotoxicity explorer and the QT safety explorer. Every chart traces to a reviewed requirement matrix, with more than 1,400 unit tests and 260 browser tests published as audit-style evidence — so "is it validated?" is now a link.

Live demos GitHub Evidence

{safetyGraphics}

Founding technical lead · ASA-DIA Interactive Safety Graphics

The open-source R/Shiny app that replaced the impenetrable safety appendix with charts a clinician can actually click. Built over five years by clinicians and technical contributors from more than two dozen organizations, and presented at the FDA Innovation Forum in 2019.

Website Demo app GitHub

More repositories, including the R/Pharma keynote experiments, on GitHub. Publication list on Google Scholar.