Values · open.csr

Values

Named numbers

Prose binds numbers by address today; the unit a writer reuses is a name. A value is declared once in library/values/values.yaml, resolved by the pipeline against the committed Analysis Results Data, and cited from prose as {{value:id}}. The build re-derives every one of them from the same ARDs the report is built from, so a value that has drifted from its source fails exactly the way a typed number does.

15values declaredeach one named, formatted and traced

13bound to an ARD rowexactly one row, or the build fails

2derived from other valuesdeclared arithmetic, re-evaluated at build

11cited in proseby name rather than by address

All 15 values were re-derived from the committed ARDs at the last assembly and matched.

The values store

Generated from library/values/values.yaml into outputs/values/values.json. Source is edited; the pipeline regenerates (design D9).

Id	Label	Value	Kind	Provenance	Cited by
randomised-n	Subjects randomised	254	ARD	t-disposition:randomised:n;group=Total outputs/t-disposition/v003/ard.json · 5a073a0 arm Total · data adsl Flow Inputs t-dispositiont-disposition:randomised:n;group=Total Function regenerate_values()resolve the address Outputs values.jsonrandomised-n = 254	TXT-E3-1002 TXT-SYN-0400 in Clinical Study Report, Abbreviated Clinical Study Report (ICH E3), Study Synopsis
treated-n	Subjects treated (safety analysis set)	254	ARD	t-disposition:treated:n;group=Total outputs/t-disposition/v003/ard.json · 5a073a0 arm Total · data adsl Flow Inputs t-dispositiont-disposition:treated:n;group=Total Function regenerate_values()resolve the address Outputs values.jsontreated-n = 254	TXT-E3-1002 TXT-SYN-0400 in Clinical Study Report, Abbreviated Clinical Study Report (ICH E3), Study Synopsis
completed-n	Subjects who completed the study	110	ARD	t-disposition:completed:n;group=Total outputs/t-disposition/v003/ard.json · 5a073a0 arm Total · data adsl Flow Inputs t-dispositiont-disposition:completed:n;group=Total Function regenerate_values()resolve the address Outputs values.jsoncompleted-n = 110	TXT-E3-1002 TXT-SYN-0400 in Clinical Study Report, Abbreviated Clinical Study Report (ICH E3), Study Synopsis
discontinued-n	Subjects who discontinued	144	ARD	t-disposition:discontinued:n;group=Total outputs/t-disposition/v003/ard.json · 5a073a0 arm Total · data adsl Flow Inputs t-dispositiont-disposition:discontinued:n;group=Total Function regenerate_values()resolve the address Outputs values.jsondiscontinued-n = 144	TXT-E3-1002 TXT-SYN-0400 in Clinical Study Report, Abbreviated Clinical Study Report (ICH E3), Study Synopsis
completed-pct	Percentage of randomised subjects who completed	43.3	ARD	t-disposition:completed:p;group=Total outputs/t-disposition/v003/ard.json · 5a073a0 arm Total · data adsl Flow Inputs t-dispositiont-disposition:completed:p;group=Total Function regenerate_values()resolve the address Outputs values.jsoncompleted-pct = 43.3	TXT-E3-1002 TXT-SYN-0400 in Clinical Study Report, Abbreviated Clinical Study Report (ICH E3), Study Synopsis
age-median-total	Median age (years), all subjects	77.0	ARD	t-demographics:age:median;group=Total outputs/t-demographics/v007/ard.json · 87af027 arm Total · data adsl Flow Inputs t-demographicst-demographics:age:median;group=Total Function regenerate_values()resolve the address Outputs values.jsonage-median-total = 77.0	—
female-n-total	Female subjects	143	ARD	t-demographics:sex:n;group=Total;variable_level=F outputs/t-demographics/v007/ard.json · 87af027 arm Total · data adsl Flow Inputs t-demographicst-demographics:sex:n;group=Total;variable_level=F Function regenerate_values()resolve the address Outputs values.jsonfemale-n-total = 143	—
ae-any-n-total	Subjects with at least one adverse event	218	ARD	t-ae-overview:any_ae:n;group=Total outputs/t-ae-overview/v003/ard.json · c428956 arm Total · data adsl, adae Flow Inputs t-ae-overviewt-ae-overview:any_ae:n;group=Total Function regenerate_values()resolve the address Outputs values.jsonae-any-n-total = 218	TXT-E3-1002 TXT-SYN-1102 in Clinical Study Report, Abbreviated Clinical Study Report (ICH E3), Study Synopsis
ae-any-n-placebo	Subjects with at least one adverse event (Placebo)	65	ARD	t-ae-overview:any_ae:n;group=Placebo outputs/t-ae-overview/v003/ard.json · c428956 arm Placebo · data adsl, adae Flow Inputs t-ae-overviewt-ae-overview:any_ae:n;group=Placebo Function regenerate_values()resolve the address Outputs values.jsonae-any-n-placebo = 65	TXT-SYN-1102 in Study Synopsis
ae-any-n-low	Subjects with at least one adverse event (Xanomeline Low Dose)	77	ARD	t-ae-overview:any_ae:n;group=Xanomeline Low Dose outputs/t-ae-overview/v003/ard.json · c428956 arm Xanomeline Low Dose · data adsl, adae Flow Inputs t-ae-overviewt-ae-overview:any_ae:n;group=Xanomeline Low Dose Function regenerate_values()resolve the address Outputs values.jsonae-any-n-low = 77	—
ae-any-n-high	Subjects with at least one adverse event (Xanomeline High Dose)	76	ARD	t-ae-overview:any_ae:n;group=Xanomeline High Dose outputs/t-ae-overview/v003/ard.json · c428956 arm Xanomeline High Dose · data adsl, adae Flow Inputs t-ae-overviewt-ae-overview:any_ae:n;group=Xanomeline High Dose Function regenerate_values()resolve the address Outputs values.jsonae-any-n-high = 76	—
ae-any-pct-high	Percentage of high-dose subjects with at least one adverse event	90.5	ARD	t-ae-overview:any_ae:p;group=Xanomeline High Dose outputs/t-ae-overview/v003/ard.json · c428956 arm Xanomeline High Dose · data adsl, adae Flow Inputs t-ae-overviewt-ae-overview:any_ae:p;group=Xanomeline High Dose Function regenerate_values()resolve the address Outputs values.jsonae-any-pct-high = 90.5	TXT-SYN-1102 in Study Synopsis
safety-n-high	Subjects in the safety analysis set (Xanomeline High Dose)	84	ARD	t-ae-overview:any_ae:N;group=Xanomeline High Dose outputs/t-ae-overview/v003/ard.json · c428956 arm Xanomeline High Dose · data adsl, adae Flow Inputs t-ae-overviewt-ae-overview:any_ae:N;group=Xanomeline High Dose Function regenerate_values()resolve the address Outputs values.jsonsafety-n-high = 84	TXT-SYN-1102 in Study Synopsis
ae-any-n-xanomeline	Subjects with at least one adverse event, both xanomeline arms	153	derived	sum(ae-any-n-low, ae-any-n-high) Flow Inputs ae-any-n-lownamed value ae-any-n-highnamed value Function regenerate_values()sum(…) Outputs values.jsonae-any-n-xanomeline = 153	TXT-SYN-1102 in Study Synopsis
ae-excess-high-vs-placebo	Additional subjects with an adverse event, high dose versus placebo	11	derived	difference(ae-any-n-high, ae-any-n-placebo) Flow Inputs ae-any-n-highnamed value ae-any-n-placebonamed value Function regenerate_values()difference(…) Outputs values.jsonae-excess-high-vs-placebo = 11	TXT-E3-1002 TXT-SYN-1102 in Clinical Study Report, Abbreviated Clinical Study Report (ICH E3), Study Synopsis