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17 posts · 14 releases
R/Pharma 2026 · Keynote · October Building open-source clinical trial tools with agentic AI Prepared in the open — follow the developer diary →

September 2026 1 post

August 2026 1 post · 3 releases

July 2026 4 posts · 10 releases

  • safety.viz v1.5.0 Participant Profile drill-down on six charts, the Hepatic ALT Waterfall, an eDISH migration Sankey NotesDemoWalkthrough
  • gsm.safety v1.0.0 First stable release: nine safety.viz charts as htmlwidgets, with demo data and gsm workflows NotesDemo
  • safety.viz v1.4.1 Consistent QT demo data; hep-explorer and qt-explorer share one view selector NotesDemo
  • safety.viz v1.4.0 QT Safety Explorer, phase 1: Δ/ΔΔ central tendency with CIs, outlier scatter, categorical table NotesDemo
  • R/Pharma Diary #7 — Papers → Prompts → PrototypesI demoed safety.viz for safetyGraphics’ clinical lead, Jim Buchanan, this week and asked if he had any improvements in mind, and no surprise, he had a few! Jim promptly sent a h...
  • safety.viz v1.3.1 Evidence pages show the reviewed requirement text beside each ID, checked in CI NotesDemo
  • safety.viz v1.3.0 Adverse Event Explorer: hierarchical incidence table with per-arm rates and drill-through NotesDemo
  • safety.viz v1.2.0 Hepatic Safety Explorer (eDISH) with participant drill-down, and the first clinical guide NotesDemo
  • R/Pharma Diary #6 — Obot v3: How I Used a Billion Tokens in a WeekendI introduced Obot 🍊😺 a few posts back and described how I set it up with OpenClaw and Telegram.1 My original readout — “51% fun / 49% frustrating” — still stands. That’s clearly...
  • safety.viz v1.1.0 All-measures overview for the histogram; demo data from a scripted pharmaverse pipeline NotesDemo
  • safety.viz v1.0.0 First stable release: six interactive charts with data contracts, demos and test evidence NotesDemo
  • R/Pharma Diary #5 — Introducing safety.vizMy last post laid out the plan for {safetyGraphics} v2 and ended on the obvious question: can we actually do this? Here’s the first big answer: safety.viz is live.1 A...
  • safety.viz v0.1.0 Safety-histogram pilot as a library module, plus the shared renderer shell NotesDemo
  • R/Pharma Diary #4 — safetyGraphics ❤️ gsmSo, here’s the plan for {safetyGraphics} v2.1 AI collaboration note — I outlined this post in June. Claude Code (using Fable 5) expanded my outline into a draft, and ...

June 2026 3 posts

May 2026 1 release

  • gsm.safety v0.1.0 Experimental bridge: first proof that {safetyGraphics} charts could run from {gsm} workflows Notes

April 2026 3 posts

February 2026 3 posts

  • Agentic Pattern: First Run the TestsI really like Simon Willison’s new series on agentic engineering patterns. If you’re using coding agents day-to-day, this feels like required reading:
  • Something Big is HappeningThis article, “Something Big Is Happening” from Matt Shumer, is a practical take on the current state of AI, and it very closely describes how I’ve been feeling the last few mon...
  • Five Levels of AI-Assisted DevelopmentI found this post outlining 5 levels of AI adoption (full original post here) to be very interesting. Here are the levels:

April 2023 1 post

  • Website refactor with GPT4The website for my main open source project is waaaay overdue for a refactor. Development on the project is still pretty active, but the content on the site is pretty out of dat...

March 2023 1 post

  • Shiny GPT DemoI asked ChatGPT to make me a little Issue Management Shiny App. Here’s how it went! Some of the resulting code is in this repo.

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